SCCM Resource Library-More Than Just Choosing the Aspirin Dose: Stroke Care in the ICU

Video Transcription

Video Summary

In this video, Thalia Froke, a NeuroICU Clinical Pharmacist Specialist, discusses updates on the management of acute ischemic stroke. She talks about the use of tenecteplase as a thrombolytic agent and its efficacy in acute ischemic stroke. She highlights the differences between tenecteplase and alteplase, including the fibrin-specificity and longer half-life of tenecteplase. Froke also discusses the use of dual antiplatelet therapy (DAPT) in acute ischemic stroke and mentions conflicting results on its effectiveness. She provides an overview of the agents used in DAPT, including aspirin. Froke further discusses the use of IV antiplatelets, such as Kangrelor and Eptafibatide, in neuroendovascular procedures. She compares the two agents and their onset of action, dosing, and clearance. Froke presents several studies that evaluated the use of Kangrelor and Eptafibatide in acute ischemic stroke and their outcomes. She also provides sample protocols for the use of these agents. In conclusion, Froke emphasizes the effectiveness of tenecteplase, the controversial role of DAPT, and the value of IV antiplatelet agents in high-risk patients undergoing endovascular procedures.

Asset Subtitle

Neuroscience, 2023

Asset Caption

Type: two-hour concurrent | Time Is Brain: An Update on Management and Pharmacology Strategies for Acute Neurologic Emergencies (SessionID 1202433)

Meta Tag

Content Type Presentation

Knowledge Area Neuroscience

Membership Level Professional

Membership Level Select

Tag Stroke

Year 2023

Keywords

acute ischemic stroke

tenecteplase

alteplase

dual antiplatelet therapy

IV antiplatelets

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