SCCM Resource Library-Neurosciences and the Pandemic

Pdf Summary

The article focuses on the neurologic manifestations associated with COVID-19 and emphasizes the complexity of understanding the virus's impact on the nervous system. COVID-19, caused by SARS-CoV-2, has been linked to various neurological conditions such as stroke, seizures, encephalitis, and demyelinating syndromes like multiple sclerosis. Common symptoms of the infection include anosmia and dysgeusia, which suggest early involvement of the central nervous system. Several mechanisms for neural infection have been proposed, including transnasal infection, blood-brain barrier breach, and hyperinflammatory toxicity.<br /><br />The article highlights a critical need to study these complications further, leading to the creation of the Global Consortium to Study Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID). This international study aims to gather real-time data on neurological complications in COVID-19 patients, involving over 450 centers across 60 countries. The research adopts a tiered approach, from acute symptom data in Tier 1 to long-term outcomes and advanced diagnostics in Tiers 2 and 3.<br /><br />Vanderbilt University is also conducting studies on long-term cognitive dysfunction and psychological outcomes in COVID-19 survivors. The article stresses collaboration with international organizations and ongoing studies to understand COVID-19's pathophysiology better, aiming to improve diagnostic and treatment approaches.<br /><br />The pandemic has impacted neurologic critical care training, altering medical education with a shift towards virtual learning and innovative training methods. The transition to virtual platforms has expanded learning opportunities and led to a unique hands-on experience in a pandemic setting. The article concludes by acknowledging the enduring influence of this experience on medical education and future pandemic preparedness.

Asset Subtitle

Neuroscience, Professional Development and Education, 2020, 00:08:17

Asset Caption

This article was first published in the Fall 2020 issue of Critical Connections. We have much to elucidate on the neurologic manifestations associated with COVID-19. Reports have been published linking severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to stroke, seizure, encephalitis, and both central and peripheral demyelination. Various forms of encephalopathies encompassing alteration of consciousness, psychosis, and neurocognit ive impairment have been reported. Furthermore, there is concern that SARS-CoV-2 may play a role in multiple sclerosis pathogenicity based on animal models and postmortem brain examinations. Critical Connections is the critical care industry’s only newsmagazine, provides information on cutting-edge topics in critical care useful to the entire multiprofessional team. Authors: Rajeev K. Garg, MD, MS Anna Karpenko, MD Rhonda S. Cadena, MD,Rajeev K. Garg, MD, MS Anna Karpenko, MD Rhonda S. Cadena, MD

Meta Tag

Content Type Article

Knowledge Area Neuroscience

Knowledge Area Professional Development and Education

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Education

Tag Fellowship Training

Year 2020

Keywords

COVID-19

neurological manifestations

SARS-CoV-2

stroke

anosmia

Global Consortium

neurological complications

Vanderbilt University

virtual learning

pandemic preparedness

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