SCCM Resource Library-Norepinephrine Challenges

Video Transcription

Video Summary

Brittany Bissell Turpin, an advanced clinical pharmacist, addressed the challenges in reporting norepinephrine concentrations in critical care. She highlighted the variability in norepinephrine salt formulations used worldwide, including bitartrate and tartrate in the U.S. and tartrate and hydrochloride elsewhere. The discrepancy in reporting either salt or base concentrations can lead to inconsistent norepinephrine dosing, impacting research, clinical guidelines, and patient care. Issues arise especially in multinational studies, where differing dosage standards can lead to heterogeneous patient enrollment and skewed trial results. This variability poses potential risks in clinical settings, such as inaccurate prognostication and inconsistent application of treatment protocols. Turpin emphasized the importance of consistent dosing standards across centers to avoid these discrepancies and improve both research outcomes and clinical practice. Acknowledging her collaborative panel, she encouraged further attention to this critical issue.

Asset Caption

One-Hour Concurrent Session | ESICM/SCCM Joint Session: Surviving Sepsis Campaign Research Priorities and Norepinephrine Challenges

Meta Tag

Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

norepinephrine

clinical pharmacist

dosing standards

multinational studies

patient care

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