SCCM Resource Library-November Journal Club: Spotlight on Pharmacy (2021)

Video Transcription

Video Summary

The Journal Club Spotlight on Pharmacy webcast featured three presentations. The first presentation discussed the effects of vasopressin and methylprednisolone on patients with in-hospital cardiac arrest. The study found that the combination of vasopressin and methylprednisolone increased the probability of return of spontaneous circulation (ROSC) in patients compared to placebo or standard care. However, there was no significant improvement in survival or neurological function. The second presentation focused on the effect of early sedation with dexmedetomidine on body temperature in critically ill patients. The study found that dexmedetomidine did not significantly increase body temperature compared to usual care. However, there was a higher incidence of mild and severe hyperthermia in the dexmedetomidine group. The third presentation discussed the FREEDA trial, which compared a non-immunogenic recombinant staphlokinase to alteplase for the management of acute ischemic stroke. The study found that staphlokinase was non-inferior to alteplase in terms of safety and efficacy. Overall, the results of these studies provide valuable insights into the use of vasopressin and methylprednisolone, dexmedetomidine, and staphlokinase in clinical practice.

Asset Subtitle

Pharmacology, Cardiovascular, Resuscitation, 2021

Asset Caption

"The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research.

Follow the conversation at #SCCMCPPJC."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Cardiovascular

Knowledge Area Resuscitation

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Tag Vasoactive Agents

Tag Cardiac Arrest

Tag Return of Spontaneous Circulation ROSC

Year 2021

Keywords

Journal Club Spotlight on Pharmacy

vasopressin

methylprednisolone

in-hospital cardiac arrest

return of spontaneous circulation

dexmedetomidine

body temperature

hyperthermia

FREEDA trial

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