SCCM Resource Library-November Journal Club: Spotlight on Pharmacy (2022)

Video Transcription

Video Summary

In this Journal Club Spotlight on Pharmacy webcast, three presenters discuss different topics related to pharmacy in critical care. The first presenter discusses the use of aggressive or moderate fluid resuscitation in acute pancreatitis. The presenter reviews the literature and guidelines surrounding fluid resuscitation in acute pancreatitis and presents the findings of a trial that compared aggressive and moderate fluid resuscitation in patients with acute pancreatitis. The trial found no difference in outcomes between the two groups, but did find that the aggressive fluid resuscitation group had a higher risk of volume overload. The second presenter discusses the use of continuous infusion versus intermittent infusion of vancomycin in critically ill patients undergoing continuous veno-venous hemofiltration. The presenter reviews the literature on this topic and presents the findings of a prospective interventional study that compared the two methods of vancomycin administration. The study found that continuous infusion resulted in higher rates of target attainment compared to intermittent infusion. The third presenter discusses the use of acetazolamide in acute decompensated heart failure with volume overload. The presenter reviews the current guidelines for the management of acute decompensated heart failure and presents the findings of a recent trial that evaluated the use of acetazolamide in patients with acute decompensated heart failure. The trial found that the addition of acetazolamide to a loop diuretic regimen was associated with a higher incidence of successful decongestion within three days. Based on the findings of this trial, the presenter suggests that it may be reasonable to consider adding acetazolamide early to the decongestion plan.

Asset Subtitle

Pharmacology, Resuscitation, 2022

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Resuscitation

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Professional

Membership Level Select

Tag Antibiotics

Tag Fluids Resuscitation Management

Year 2022

Keywords

critical care

fluid resuscitation

acute pancreatitis

continuous infusion

intermittent infusion

vancomycin

continuous veno-venous hemofiltration

acetazolamide

acute decompensated heart failure

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