SCCM Resource Library-October Journal Club Spotlight on Pharmacy (2024)

Video Transcription

Video Summary

The Journal Club Spotlight on Pharmacy webcast featured three pharmacology specialists presenting on recent clinical trials. The first speaker, Rachel Oh, highlighted the FLUGRA study, which examined fludrocortisone dosing in septic shock. The study found no significant difference in shock resolution times between groups receiving various doses of fludrocortisone combined with hydrocortisone, though the trial was underpowered due to early termination. Joanna Nixon, the second speaker, discussed the STOP or NOT trial, which investigated whether to continue or discontinue renin-angiotensin system inhibitors before major non-cardiac surgery. The study found no significant difference in postoperative complications between the two groups, suggesting individualized management based on specific patient factors might be optimal. Finally, Hannah Frank presented on the adjunctive use of argatroban or eptifibatide in patients undergoing thrombolysis for acute ischemic stroke. The study concluded that neither drug improved functional outcomes or safety, and argatroban was associated with higher mortality. Overall, the webcast provided valuable insights into the evolving pharmacological management in critical care settings, emphasizing the need for individualized treatment plans based on current, robust clinical evidence.

Asset Subtitle

Pharmacology, Sepsis, Neuroscience, 2024

Asset Caption

The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussions and in-depth presentations on the latest research. Registered attendees receive complimentary access to the webcast for one year.

Meta Tag

Content Type Webcast

Knowledge Area Sepsis

Knowledge Area Procedures

Knowledge Area Neuroscience

Membership Level Professional

Membership Level Select

Tag Surgery

Tag Stroke

Tag Sepsis

Year 2024

Keywords

Webcast

Sepsis

Procedures

Neuroscience

Surgery

Stroke

Professional

Select

2024

FLUGRA study

septic shock

fludrocortisone

STOP or NOT trial

renin-angiotensin inhibitors

non-cardiac surgery

thrombolysis

acute ischemic stroke

individualized treatment

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