SCCM Resource Library-October Journal Club Webcast: Spotlight on Pharmacy (2021)

Video Transcription

Video Summary

In this video, three presenters discuss different topics related to critical care medicine. The first presenter talks about the effect of continuous infusion hypertonic saline compared to standard of care on six-month neurological outcomes in patients with traumatic brain injury. The research question from the COBE clinical trial was to assess the impact of continuous infusion 20% hypertonic saline compared to standard of care on neurological outcomes at six months. The trial found that there was no significant improvement in clinical outcomes with the use of hypertonic saline. The second presenter discusses the treatment of multisystem inflammatory syndrome in children (MIS-C) with IVIG and steroids. The study found that IVIG and steroids were associated with a lower risk of cardiovascular dysfunction compared to IVIG alone. However, there was no significant difference in neurologic outcomes at six months. The third presenter reviews the prescribing practices of valproic acid for agitation and delirium in the intensive care unit (ICU) . The study found that valproic acid may improve delirium resolution, but may not resolve agitation. It also showed a decrease in the use of other sedative agents. Overall, the study concluded that valproic acid may be useful in the management of hyperactive delirium, but more research is needed to assess its safety and long-term outcomes.

Asset Subtitle

Pharmacology, Neuroscience, Trauma, 2021

Asset Caption

"The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research.

Follow the conversation at #SCCMCPPJC."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Neuroscience

Knowledge Area Trauma

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Associate

Membership Level Select

Membership Level Professional

Tag Fluids Resuscitation Management

Tag Traumatic Brain Injury TBI

Year 2021

Keywords

critical care medicine

continuous infusion hypertonic saline

neurological outcomes

traumatic brain injury

multisystem inflammatory syndrome in children

IVIG

steroids

valproic acid

agitation

delirium

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