SCCM Resource Library-Overview of TAXI-CAB Methodology and General Guidance for Plasma and Platelet Transfusions in Critically Ill Children

Overview of TAXI-CAB Methodology and General Guidance for Plasma and Platelet Transfusions in Critically Ill Children

Video Transcription

Video Summary

In this video, Marian Mellis discusses the recent plasma and platelet transfusion guidance created for critically ill children by the Taxi Cab group. The Taxi Cab initiative aims to provide evidence-based recommendations for transfusion and blood management practices in these patients. The guidance was developed through a systematic review of the literature and consensus among a diverse group of experts. The recommendations include using leukocyte-reduced cellular blood components in critically ill neonatal and pediatric patients, using RHD-positive platelets in RHD-negative patients if RHD-negative platelets are not available, considering viscoelastic monitoring and institution-specific transfusion algorithms in children undergoing cardiopulmonary bypass surgery, and monitoring overall clinical context when deciding to transfuse plasma and platelets. Decision trees were also developed to guide transfusion decisions based on patient diagnoses and bleeding severity. The guidance will be updated every five years, and future involvement in the initiative is welcome.

Asset Subtitle

Hematology, Pediatrics, 2022

Asset Caption

The TAXI-CAB initiative assessed current literature with the goal of generating evidence-based recommendations and guidelines for plasma and platelet transfusion practices in critically ill children.

Meta Tag

Content Type Presentation

Knowledge Area Hematology

Knowledge Area Pediatrics

Knowledge Level Advanced

Membership Level Select

Tag Transfusion

Tag Pediatrics

Year 2022

Keywords

plasma transfusion

platelet transfusion

critically ill children

Taxi Cab group

blood management practices

transfusion guidance

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