SCCM Resource Library-Patterns of Pathogen-Induced Immunosupression

Patterns of Pathogen-Induced Immunosupression

Video Transcription

Video Summary

The talk outlines the complexities of host-pathogen interactions in critical illness, focusing on sepsis and SARS-CoV-2. It emphasizes the interplay between the innate and adaptive immune responses, noting that pathogens can evade immunity, leading to dysregulated responses and susceptibility to secondary infections. Subclassification of patients is highlighted as crucial for targeted immunotherapy. The presenter identifies translational gaps, such as choosing immune profiling tools, understanding genetic and microbial interactions, and assessing compartmentalized immune responses. The push towards precision medicine in critical care involves integrating classification, point-of-care assays, and scalable immune-modulatory therapies.

Asset Caption

One-Hour Concurrent Session | Induced Immunosuppression in the ICU

Meta Tag

Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

host-pathogen interactions

sepsis

immune responses

precision medicine

immunotherapy

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