SCCM Resource Library-Physiologic Subphenotypes in ARDS: Can They Make a Difference?

Video Transcription

Video Summary

In this talk, the speaker discusses the concept of physiologic subphenotypes in ARDS (Acute Respiratory Distress Syndrome). They highlight that there are various ways to phenotype ARDS, including clinically obvious phenotypes like risk factors, lung injury type, severity, and COVID-19 versus typical ARDS. The speaker focuses on physiologic subphenotypes, specifically respiratory physiology, and mentions parameters such as severity, PF ratio, lung compliance, driving pressure, and data-driven algorithms. They discuss the potential differences in treatment response among different subphenotypes and provide examples from studies on lung compliance, ECMO, and COVID-19. The speaker also briefly mentions the role of non-pulmonary physiology in defining phenotypes. They highlight the need for further research to incorporate multidimensional data and conduct prospective studies with detailed physiologic phenotyping to better understand how to tailor treatment for patients with ARDS.

Asset Subtitle

Pulmonary, 2023

Asset Caption

Type: one-hour concurrent | Targeted Treatments for a Devastating Disease: What Subphenotypes of ARDS May Mean for Your ICU (SessionID 1227925)

Meta Tag

Content Type Presentation

Knowledge Area Pulmonary

Membership Level Professional

Membership Level Select

Tag Acute Respiratory Distress Syndrome ARDS

Year 2023

Keywords

physiologic subphenotypes

ARDS

respiratory physiology

treatment response

lung compliance

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