SCCM Resource Library-Post-Spinal Cord Injury Therapeutic Effects of Human Neural Stem Cells

Video Transcription

Video Summary

In this conference, the speaker discusses the therapeutic effects of human neural stem cells in post-spinal cord injury. Neural stem cells have the potential to be used in treating neurological problems, including neurotrauma. The speaker explains that the brain contains two neurogenic zones that produce neural stem cells, and these cells have the ability to migrate and become neurons. The speaker's lab developed a novel technology using synthetic materials to scaffold neural stem cells and transplant them into spinal cord injuries. The results showed that the rats experienced robust recovery of hind limb locomotion. The donor cells survived long-term in the host spinal cord and were found to have multiple functions, including expressing trophic factors, reducing inflammation, suppressing scar formation, and helping to reactivate neural circuits. The speaker proposes a new neurobiology concept that highlights the functional multipotency of stem cells. This research has the potential to lead to new treatments for neurotrauma.

Asset Subtitle

Neuroscience, Transplant, 2022

Asset Caption

This session will review the exciting frontier of stem cell therapy for acute neurological injuries, including global anoxic injury, stroke, and spinal cord injury.

Meta Tag

Content Type Presentation

Knowledge Area Neuroscience

Knowledge Area Transplant

Knowledge Level Advanced

Membership Level Select

Tag Spinal Cord Injury

Tag Stem Cells

Year 2022

Keywords

neural stem cells

spinal cord injury

therapeutic effects

neurotrauma

functional multipotency

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