SCCM Resource Library-Pro/Con: Are Sepsis Outcomes Really Modifiable?

Video Transcription

Video Summary

The transcript is a debate between Krista Schorr and Emily Brandt on the modifiability of sepsis outcomes. Schorr argues that the needle can be moved on sepsis outcomes by using research design and data usage to identify patients, incorporating artificial intelligence and big data, and considering long-term outcomes and goals of care for sepsis survivors. Brandt, on the other hand, argues that focusing on sepsis outcomes is problematic and presents three counterfactuals. Firstly, she suggests that a one-size-fits-all approach may not be ideal for the heterogeneous syndrome of sepsis, and individualized therapies should be considered. Secondly, she highlights the disparities in sepsis trial recruitment and the need for more inclusive representation of patients. Finally, she challenges the notion that mortality is the worst outcome and calls for greater focus on post-sepsis symptoms and the long-term impact on patients and families. Brandt emphasizes the need for palliative care strategies and enhanced trial approaches to address these challenges. Both speakers call for continued research and innovation to improve outcomes in sepsis.

Asset Subtitle

Sepsis, Worldwide Data, 2022

Asset Caption

Morbidity and mortality are substantial in sepsis patients. However, underlying comorbidities predisposing to sepsis may be dominant contributors to poor outcomes. This pro/con debate will explore the evidence regarding the degree to which sepsis outcomes may be modifiable.

Learning Objectives:
-Debate evidence from the literature regarding risks of adverse outcomes in sepsis patients attributable to the sepsis event versus comorbid conditions
-Evaluate whether sepsis clinical trial results can be used to assess the modifiability of sepsis outcomes
-Discuss how the evidence may best inform both clinical practice and future clinical trials to improve sepsis outcomes

Meta Tag

Content Type Presentation

Knowledge Area Sepsis

Knowledge Area Worldwide Data

Knowledge Level Intermediate

Knowledge Level Advanced

Learning Pathway Sepsis Resources

Membership Level Select

Tag Sepsis

Tag Epidemiology Outcomes

Year 2022

Keywords

sepsis outcomes

research design

data usage

artificial intelligence

long-term outcomes

individualized therapies

disparities in sepsis trial recruitment

palliative care strategies

Sepsis

Epidemiology Outcomes

Presentation

Select

2022

Worldwide Data

Intermediate

Advanced

Sepsis Resources

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