Pro/Con: Block It or Drop It? Debating Neuromuscular Blockade for Acute Respiratory Distress Syndrome
Back to course
Video Transcription
Video Summary
Asset Subtitle
Pharmacology, Pulmonary, 2022
Asset Caption
The use of neuromuscular blocking agents (NMBAs) has been established as part of the treatment strategy for patients with acute respiratory distress syndrome (ARDS). However, the optimal approach to dosing NMBAs for patients is still controversial. The 2016 Society of Critical Care Medicine guidelines on the use of NMBAs did not discuss whether to utilize a continuous infusion (titrated or flat dose) or intermittent doses. The two major trials to date, ACURASYS and ROSE-PETAL, both used a continuous infusion (flat dose) approach. However, with the numerous adverse effects associated with NMBAs, an intermittent strategy could be considered to reduce the total dose and lessen these adverse effects. Furthermore, the ROSE trial did not show benefit with a continuous infusion (flat dose) approach. This session will comprise two pro/con sessions that will discuss the therapeutic yield of neuromuscular blockade, dosing approaches to NMBAs in ARDS, and the monitoring and potential long-term sequelae of NMBAs. Learning Objectives: -Explore the controversies surrounding the therapeutic benefit of neuromuscular blockade for acute respiratory distress syndrome (ARDS) -Compare administration strategies for neuromuscular blockade including intermittent doses and continuous infusions -Compare and contrast efficacy and discrepancies in the literature on paralysis in patients with ARDS
Meta Tag
Content Type Presentation
Knowledge Area Pharmacology
Knowledge Area Pulmonary
Knowledge Level Intermediate
Knowledge Level Advanced
Membership Level Select
Tag Pharmacology
Tag Acute Respiratory Distress Syndrome ARDS
Year 2022
Keywords
neuromuscular blockade
acute respiratory distress syndrome
ARDS
dosing strategies
ACURISIS trial
ROSE trial
continuous infusion
mortality
sedation
evidence-based decision-making

   

   
 
Society of Critical Care Medicine

500 Midway Drive
Mount Prospect, IL 60056 USA

Phone: +1 847 827-6888
Fax: +1 847 439-7226
Email: support@sccm.org


Contact Us

About SCCM

Newsroom

Advertising & Sponsorship

DONATE


MySCCM

LearnICU

Patients & Families

Surviving Sepsis Campaign

Critical Care Societies Collaborative


kisspng-facebook-social-media-computer-icons-linkedin-soci-gray-5ac493cf1c2975.7867418415228323351154  - KW Symphony    Gray twitter 3 icon - Free gray social icons    Gray linkedin 3 icon - Free gray site logo icons    Gray instagram icon - Free gray social icons    YouTube Icon Gray Box - HONOR VETERANS NOW

GET OUR NEWSLETTER






© Society of Critical Care Medicine. All rights reserved.   |    Privacy Statement    |    Terms & Conditions
The Society of Critical Care Medicine, SCCM, and Critical Care Congress are registered trademarks of the Society of Critical Care Medicine.



Android App Download IOS App Download Powered By