SCCM Resource Library-RSV in Critically Ill Children: Therapy and Management

Video Transcription

Video Summary

The webcast discussed RSV (respiratory syncytial virus) in critically ill children. The moderator, Dr. Bria Coates, introduced herself as an assistant professor of pediatrics at Northwestern University. She presented the outline of the topics to be discussed during the webcast, including risk factors for severe RSV infections, the pathophysiology of RSV infections on the cellular level, gene expression in the nose of children with RSV infections, long-term consequences of RSV infections, current treatments in the ICU, and new developments in therapeutics and vaccines. The first speaker, Andrew Prigge, discussed his research on gene expression in the nose of children with RSV infections and its correlation with clinical outcomes. He found that increased damage to ciliated cells in the airways was associated with longer hospital stays. The second speaker, Briseida Morales, discussed current treatment options for RSV infections in the ICU, including high-flow nasal cannula, bronchodilators, hypertonic saline, and suctioning. She also mentioned the potential of the following advancements in RSV management: percussive ventilation for secretion clearance, azithromycin for its antiviral and anti-inflammatory effects, long-acting monoclonal antibodies for prevention, and the development of an RSV vaccine. The speakers emphasized the need for further research to understand the factors that contribute to severe RSV infections and to identify therapeutic targets that could modify the disease course.

Asset Subtitle

Pulmonary, Pediatrics, 2023

Asset Caption

Review the pathophysiology of respiratory syncytial virus (RSV) infection and how it can drive critical illness in young children in this complimentary SCCM webcast. Subject matter experts discuss potential therapies and management strategies for critical RSV infections and explore the implications of future RSV vaccines.

Meta Tag

Content Type Webcast

Knowledge Area Pulmonary

Knowledge Area Pediatrics

Knowledge Level Foundational

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Nonmember

Membership Level Associate

Membership Level Professional

Membership Level Select

Tag Respiratory Syncytial Virus RSV

Tag Pediatrics

Year 2023

Keywords

RSV

respiratory syncytial virus

critically ill children

gene expression

treatments

ICU

therapeutics

vaccines

severe infections

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