SCCM Resource Library-Reducing Antibiotic Treatment Duration for Ventilator-Associated Pneumonia: A Multicenter, Individually Randomized, Open-Label, Non-Inferiority Trial (REGARD-VAP) (Lancet Respiratory Medicine)

Reducing Antibiotic Treatment Duration for Ventilator-Associated Pneumonia: A Multicenter, Individually Randomized, Open-Label, Non-Inferiority Trial (REGARD-VAP) (Lancet Respiratory Medicine)

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Video Transcription

Video Summary

The video discusses a study on reducing antibiotic treatment duration for ventilator-associated pneumonia (VAP) in six hospitals across Nepal, Singapore, and Thailand, sponsored by Oxford University. The study compared short-course and long-course antibiotic therapies, revealing no significant differences in 60-day mortality or pneumonia recurrence. The short-course treatment showed fewer side effects, lower antibiotic use, and potentially reduced risk of antimicrobial resistance. The research, published in Lancet Respiratory Medicine, emphasizes personalized treatment durations based on simple clinical criteria, suggesting applicability in low- and middle-income settings.

Asset Caption

One-Hour Concurrent Session | Late-Breaking Studies Affecting Patient Outcomes II

Meta Tag

Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

ventilator-associated pneumonia

antibiotic treatment duration

antimicrobial resistance

personalized treatment

Lancet Respiratory Medicine

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