SCCM Resource Library-SCCM-Weil Research Grant Recipient Presentation: Exploring Changes in Peritoneal Macrophage Composition and Function During Sepsis

SCCM-Weil Research Grant Recipient Presentation: Exploring Changes in Peritoneal Macrophage Composition and Function During Sepsis

Back to course

Video Transcription

Video Summary

The talk explores changes in peritoneal macrophage composition and function during sepsis. Tissue resident macrophages exist in most tissues in the body and play a role in cleaning up dead cells and responding to infection or tissue damage. In the peritoneal cavity, there are two populations of macrophages: large peritoneal macrophages (LPM) and small peritoneal macrophages (SPM). During an inflammatory response, LPM disappear from the peritoneal wash while monocytes rapidly infiltrate and differentiate into SPM. The study analyzes how myeloid cells change during abdominal sepsis and sterile abdominal surgery, and investigates the relationship between monocyte infiltration and sepsis survival.

Asset Subtitle

Professional Development and Education, Sepsis, 2023

Asset Caption

Type: one-hour concurrent | ACCM Distinguished Investigator Award and SCCM-Weil Research and Discovery Grant Recipient Presentations (SessionID 9900004)

Meta Tag

Content Type Presentation

Knowledge Area Professional Development and Education

Knowledge Area Sepsis

Membership Level Professional

Membership Level Select

Tag Medical Education

Tag Sepsis

Year 2023

Keywords

peritoneal macrophage composition

peritoneal macrophage function

sepsis

tissue resident macrophages

peritoneal cavity

	Society of Critical Care Medicine 500 Midway Drive Mount Prospect, IL 60056 USA Phone: +1 847 827-6888 Fax: +1 847 439-7226 Email: support@sccm.org	Contact Us About SCCM Newsroom Advertising & Sponsorship DONATE	MySCCM LearnICU Patients & Families Surviving Sepsis Campaign Critical Care Societies Collaborative	GET OUR NEWSLETTER
© Society of Critical Care Medicine. All rights reserved. \| Privacy Statement \| Terms & Conditions The Society of Critical Care Medicine, SCCM, and Critical Care Congress are registered trademarks of the Society of Critical Care Medicine.