SCCM Resource Library-September Journal Club: Spotlight on Pharmacy (2020)

Video Transcription

Video Summary

In this Journal Club Spotlight on Pharmacy webcast, three presenters discussed different research studies related to critical care medicine. The first presenter discussed the ACTS randomized clinical trial, which studied the effect of ascorbic acid, corticosteroids, and thiamine on organ injury and septic shock. The study found that the combination did not result in a reduction of SOFA scores during the first 72 hours after enrollment, suggesting that routine use of this combination is not supported. The second presenter discussed the acetate trial, which compared low-chloride versus high-chloride containing hypertonic solutions for the treatment of subarachnoid hemorrhage-related complications. The study found no significant difference in vasopressor requirements between the two groups, suggesting that a balanced hypertonic saline solution is a reasonable strategy for treating cerebral edema. The third presenter discussed a subgroup analysis of the SPICE-3 trial, which looked at the effect of dexmedetomidine on vasopressor requirements in patients with septic shock. The study found no significant difference in vasopressor requirements between the dexmedetomidine and usual care groups. The presenters discussed the strengths and limitations of each study and provided their conclusions and recommendations. Overall, the studies provided insights into the use of different therapies in critical care settings.

Asset Subtitle

Pharmacology, Sepsis, 2020

Asset Caption

"The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research.

Follow the conversation at #SCCMCPPJC."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Sepsis

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Pharmacology

Tag Shock

Year 2020

Keywords

critical care medicine

ACTS trial

organ injury

septic shock

SOFA scores

acetate trial

hypertonic solutions

vasopressor requirements

dexmedetomidine

	Society of Critical Care Medicine 500 Midway Drive Mount Prospect, IL 60056 USA Phone: +1 847 827-6888 Fax: +1 847 439-7226 Email: support@sccm.org	Contact Us About SCCM Newsroom Advertising & Sponsorship DONATE	MySCCM LearnICU Patients & Families Surviving Sepsis Campaign Critical Care Societies Collaborative	GET OUR NEWSLETTER
© Society of Critical Care Medicine. All rights reserved. \| Privacy Statement \| Terms & Conditions The Society of Critical Care Medicine, SCCM, and Critical Care Congress are registered trademarks of the Society of Critical Care Medicine.