SCCM Resource Library-September Journal Club: Spotlight on Pharmacy (2021)

Video Transcription

Video Summary

The Journal Club Spotlight on Pharmacy webcast discussed three different topics. The first presentation focused on comparing the efficacy and safety of two inotropic agents, milrinone, and dobutamine, in the treatment of cardiogenic shock. The study found no significant difference between the two agents in terms of mortality or clinical outcomes. The second presentation examined the dosing strategy for cystic fibrosis curium in acute respiratory distress syndrome (ARDS) . The study compared fixed-dose dosing with titrated dosing based on train-of-four monitoring. Results showed that both dosing strategies were equally effective in improving oxygenation and clinical outcomes in patients with ARDS. The third presentation discussed the use of four-factor prothrombin complex concentrate (PCC) in the reversal of factor Xa inhibitors in spontaneous or traumatic intracranial hemorrhage (ICH) . The study compared the efficacy of a low dose of 25 units per kilogram with a standard dose of 50 units per kilogram. Results showed no significant difference in hemostatic efficacy between the two dosing strategies. These findings suggest that the low dose may be an effective alternative to the standard dose for factor Xa inhibitor reversal in ICH.

Asset Subtitle

Pharmacology, Cardiovascular, 2021

Asset Caption

"The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research.

Follow the conversation at #SCCMCPPJC."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Cardiovascular

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Pharmacology

Tag Shock

Year 2021

Keywords

inotropic agents

cardiogenic shock

cystic fibrosis curium

acute respiratory distress syndrome

fixed-dose dosing

train-of-four monitoring

factor Xa inhibitors

intracranial hemorrhage

hemostatic efficacy

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