SCCM Resource Library-Star Research Presentations: Pharmacology

Video Transcription

Video Summary

Summary of the first video:<br /><br />The study focused on determining the optimal dose of anoxaparin for pediatric patients with chilothorax after cardiac surgery. Chilothorax is a condition where lymphatic fluid accumulates in the pleural space after heart surgery, potentially causing respiratory distress. The study compared anoxaparin dosing and monitoring between patients with and without chilothorax and found that those with chilothorax required higher doses of anoxaparin to achieve therapeutic anticoagulation. However, there was no difference in plasma antithrombin levels between the two groups. The researchers suggested a 10 to 30% increase in the initial anoxaparin dose for patients with chilothorax, highlighting the importance of personalized dosing strategies and close monitoring in this population.<br /><br />Summary of the second video:<br /><br />A retrospective study examined the use of ketamine in ICU patients to evaluate its effects on pain, sedation, and delirium. The study included 390 adult patients from 25 sites who received continuous infusions of ketamine. The results showed that ketamine increased the proportion of time spent in goal pain and sedation score ranges. It also reduced the need for other sedatives and opioids. However, ketamine did not have a significant effect on delirium incidence. The study concluded that ketamine is a viable option for patients who do not respond to traditional analgesics and sedatives. Further prospective randomized studies are needed to determine the overall safety and potential benefits of using ketamine in the ICU setting.

Asset Subtitle

Pharmacology, 2020

Asset Caption

The Society of Critical Care Medicine's Critical Care Congress features internationally renowned faculty and content sessions highlighting the most up-to-date, evidence-based developments in critical care medicine. This is a presentation from the 2020 Critical Care Congress held February 16-19, 2020, in Orlando, Florida, USA.

41-A Bivalirudin Anticoagulation Protocol for Neonatal Extracorporeal Membrane Oxygenation

Christopher Snyder

42-Outcomes from the PITCH Study: 4-Factor PCC in Intracranial Xa Inhibitor Coagulopathy Hemorrhages

Nathan Goad

43-Pharmacist Avoidance or Reductions in Medication Costs in Critically Ill Patients: PHARM-CRIT Study

Drayton A. Hammond

44-Enoxaparin Dose Requirement in Pediatric Patients With Chylothorax After Cardiac Surgery

Taryn Mancarella

45-Pharmacist Avoidance or Reductions in Medication Costs in Emergently Ill Patients: PHARM-EM Study

Megan A. Rech

46-Surgical Intensive Care Unit Pain Management in the Era of Intravenous Opioid Shortages

Allison Bouwma

47-Methylene Blue Versus Hydroxocobalamin for Postoperative Vasoplegia: A Retrospective Analysis

Mckenna L Jennings

48-Effects of Ketamine on Pain, Sedation, and Delirium in the Intensive Care Unit (Ketamine-ICU Study)

Christine M. Groth

Meta Tag

Content Type Presentation

Knowledge Area Pharmacology

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Anticoagulation

Tag Economics

Tag Analgesia and Sedation

Year 2020

Keywords

anoxaparin

pediatric patients

chilothorax

cardiac surgery

respiratory distress

monitoring

therapeutic anticoagulation

plasma antithrombin levels

ICU patients

ketamine

pain

sedation

delirium

continuous infusions

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