SCCM Resource Library-Stepped Wedge Cluster Randomized Trial of Small-Volume Blood Collection Tubes to Reduce Red Blood Cell Transfusion in the Intensive Care Unit (STRATUS Trial)

Stepped Wedge Cluster Randomized Trial of Small-Volume Blood Collection Tubes to Reduce Red Blood Cell Transfusion in the Intensive Care Unit (STRATUS Trial)

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Video Transcription

Video Summary

The Stratus Trial was conducted to investigate whether transitioning to small volume blood collection tubes in intensive care units (ICUs) could reduce the need for red blood cell transfusions. The trial involved 25 ICUs in Canada and included over 51,000 patients. The primary outcome measured was the number of red blood cell units transfused per patient during their ICU stay. The results showed that transitioning to small volume tubes led to a reduction in the number of transfusions, with a mean difference of 9.84 units per 100 patients. This corresponds to a potential saving of 1,500 units of red blood cells in the trial. The smaller volume tubes did not affect lab testing or the proportion of specimens with insufficient quantity. The study highlights the potential benefits of using small volume tubes in ICUs to reduce the need for red blood cell transfusions, saving resources and supporting blood supply sustainability.

Asset Subtitle

Research, Hematology, 2023

Asset Caption

Type: two-hour concurrent | Late-Breaking Studies Affecting Patient Outcomes (SessionID 9000007)

Meta Tag

Content Type Presentation

Knowledge Area Research

Knowledge Area Hematology

Membership Level Professional

Membership Level Select

Tag Outcomes Research

Tag Transfusion

Year 2023

Keywords

Stratus Trial

small volume blood collection tubes

intensive care units

red blood cell transfusions

ICU stay

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