SCCM Resource Library-Sugar-Free DKA

Video Transcription

Video Summary

The speaker, Emily Perriello, discusses euglycemic diabetic ketoacidosis (EDKA) in this video presentation. EDKA refers to a condition where patients exhibit ketosis and acidosis, but have relatively normal blood glucose levels (less than 250 mg/dL). The presentation highlights that EDKA can be caused by factors other than SGLT2 inhibitors, contrary to popular belief. The speaker discusses the pathophysiology of EDKA, which involves a combination of insulin deficiency, insulin resistance, decreased glucose availability, and increased urinary glucose excretion. Diagnosis of EDKA can be challenging, as its presentation is similar to typical DKA. Delayed recognition of EDKA is common due to its normal glucose levels, resulting in prolonged acidosis and potential complications. Treatment of EDKA involves fluid resuscitation, insulin administration, and dextrose supplementation. Prevention strategies include discontinuing SGLT2 inhibitors before potential triggers, monitoring serum ketones, and avoiding excess alcohol or low-carbohydrate diets. The speaker emphasizes the importance of early diagnosis and appropriate management of EDKA to prevent complications.

Asset Subtitle

Endocrine, 2022

Asset Caption

This session will cover new controversies in the medication management of classical disease states, touching base with our critical care roots.

Meta Tag

Content Type Presentation

Knowledge Area Endocrine

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Diabetes

Year 2022

Keywords

euglycemic diabetic ketoacidosis

EDKA

ketosis

acidosis

blood glucose levels

insulin deficiency

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