SCCM Resource Library-That's One Large Blister: What to Do With TEN/SJS

Video Transcription

Video Summary

In this video, Dr. Laura Johnson discusses Stevens-Johnson syndrome (SJS), a severe and potentially life-threatening skin reaction. She explains that SJS is a rare condition that primarily affects the skin but can also affect mucous membranes such as the eyes, mouth, and genital area. The condition is thought to be a type 4 hypersensitivity reaction and usually occurs as a result of certain medications or infections. Diagnostic criteria for SJS are based on the extent of skin involvement, with less than 10% involvement classified as SJS, greater than 30% as toxic epidermal necrolysis (TEN), and 10-30% as an overlap between the two. Early diagnosis and referral to intensive care units and dermatologists are key to improving outcomes. Treatment involves discontinuing the inciting agent and providing supportive care, as well as potentially using steroids, IVIG, TNF-alpha inhibitors, and cyclosporine to minimize skin damage. Dr. Johnson also highlights the long-term implications of SJS, including ocular problems, infertility, sexual dysfunction, and mental health issues.

Asset Subtitle

Integument, 2023

Asset Caption

Type: one-hour concurrent | Can You Take a Look at This Rash? (SessionID 1119177)

Meta Tag

Content Type Presentation

Knowledge Area Integument

Membership Level Professional

Membership Level Select

Tag Dermatology

Year 2023

Keywords

Stevens-Johnson syndrome

SJS

skin reaction

mucous membranes

type 4 hypersensitivity reaction

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