SCCM Resource Library-The Effect of Intensive Care-Tailored Computerized Decision Support Alerts on Administration of High-Risk Drug Combinations and Their Monitoring: A Cluster Randomized Stepped-Wedge Trial (Lancet)

The Effect of Intensive Care-Tailored Computerized Decision Support Alerts on Administration of High-Risk Drug Combinations and Their Monitoring: A Cluster Randomized Stepped-Wedge Trial (Lancet)

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Video Summary

The study evaluated tailoring clinical decision support systems (CDSS) for drug-drug interaction (PDDI) alerts in ICUs to reduce alert fatigue and improve monitoring. Conducted in the Netherlands with nine ICUs, the trial tested the hypothesis that customizing alerts would increase specificity, resulting in a 12-14% reduction in high-risk drug combinations and a 9% increase in appropriate monitoring. The study underscored the necessity of adapting CDSS to different hospital wards, suggesting that tailored alerts improve effectiveness. It emphasized the need for more research in diverse clinical settings to further refine alert systems.

Asset Caption

One-Hour Concurrent Session | Late-Breaking Studies Affecting Patient Outcomes I

Meta Tag

Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

clinical decision support systems

drug-drug interaction alerts

ICU alert fatigue

customized CDSS

hospital ward adaptation

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