SCCM Resource Library-The Use of Whole Blood for Severe Bleeding

Video Transcription

Video Summary

In this video, Dr. Phil Spinella discusses the use of whole blood for severe traumatic bleeding. Whole blood, or components in a one-to-one-to-one ratio, is used in a bundle of care called damage control resuscitation to reduce death from hemorrhagic shock. Hemostatic resuscitation involves pushing blood forward in resuscitation to limit survivable bleeding. Treating patients with hemorrhagic shock in the pre-hospital phase is crucial, as the majority of hemorrhagic deaths occur in this phase. While whole blood can be warm and fresh or cold-stored, the focus is on low titer Group O whole blood, which has advantages over component therapy, such as increased storage duration and reduced risk of ABO incompatibility. Studies have shown that whole blood is associated with improved survival, reduced blood product utilization, and no difference in organ failure. Its utilization is increasing in trauma centers and is being considered for non-trauma patients as well. However, the potential risk of RH isoimmunization in women of childbearing age remains a concern. Future developments include a DARPA-funded program to make a dried whole blood product.

Asset Subtitle

Hematology, 2022

Asset Caption

The Society of Critical Care Medicine's Critical Care Congress features internationally renowned faculty and content sessions highlighting the most up-to-date, evidence-based developments in critical care medicine. This is a presentation from the 2022 Critical Care Congress held from April 18-21, 2022.

Meta Tag

Content Type Presentation

Knowledge Area Hematology

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Hemorrhage

Tag Transfusion

Year 2022

Keywords

whole blood

severe traumatic bleeding

damage control resuscitation

hemorrhagic shock

hemostatic resuscitation

pre-hospital phase

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