SCCM Resource Library-Therapeutic Plasma Exchange in Children With Acute Liver Failure: Is It Time for Incorporation Into the ALF Armamentarium?

Therapeutic Plasma Exchange in Children With Acute Liver Failure: Is It Time for Incorporation Into the ALF Armamentarium?

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Video Transcription

Video Summary

In this video, the speaker discusses therapeutic plasma exchange and its role in treating acute liver failure. They explain that therapeutic plasma exchange involves the removal of plasma and the replacement with a replacement fluid. It can rapidly and efficiently reduce pathogenic substances in the blood. However, it does not treat the underlying cause of liver failure. The speaker goes on to discuss studies that have shown the potential benefits of therapeutic plasma exchange in improving patient outcomes. They also discuss the appropriate prescription and duration of the therapy, noting that there is limited evidence or guidelines in this area. The speaker also explores the concept of high-volume plasma exchange and its potential benefits. Additionally, they discuss the use of hybrid extracorporeal therapies, which combine plasma exchange with continuous renal replacement therapy. The speaker concludes by emphasizing the importance of therapeutic plasma exchange in the treatment of acute liver failure and encourages further research in this area.

Asset Subtitle

GI and Nutrition, Pediatrics, Hematology, 2023

Asset Caption

Type: two-hour concurrent | Liver Failure in the Pediatric ICU: Current Controversies (Pediatrics) (SessionID 1191837)

Meta Tag

Content Type Presentation

Knowledge Area GI and Nutrition

Knowledge Area Pediatrics

Knowledge Area Hematology

Membership Level Professional

Membership Level Select

Tag Liver

Tag Pediatrics

Tag Transfusion

Year 2023

Keywords

therapeutic plasma exchange

acute liver failure

replacement fluid

pathogenic substances

patient outcomes

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