SCCM Resource Library-Thought Leader: What Are the Gaps in Sepsis Treatment

Video Transcription

Video Summary

The speaker discusses the challenges and knowledge gaps in the treatment of patients with sepsis and septic shock. They highlight the high mortality rates associated with sepsis and the slow improvement in mortality rates for septic shock. The speaker points out the variability in treatment practices and the implications this has on patient outcomes. They discuss the controversies surrounding initial fluid resuscitation volume and the need for high-quality studies in this area. The speaker also addresses the use of vasopressors, specifically norepinephrine, epinephrine, and vasopressin. They highlight the lack of clear evidence on the optimal approach and the need for further research. The speaker emphasizes the importance of identifying treatment-responsive sub-phenotypes in order to personalize therapy for sepsis patients. They propose the use of prognostic enrichment and predictive enrichment in clinical trials to improve patient outcomes and revolutionize care delivery. In conclusion, the speaker emphasizes the need for more high-quality research in the treatment of sepsis and septic shock.

Asset Subtitle

Sepsis, 2023

Asset Caption

Type: thought leader | Thought Leader: What Are the Gaps in Sepsis Treatment? (SessionID 9990001)

Meta Tag

Content Type Presentation

Knowledge Area Sepsis

Membership Level Professional

Membership Level Select

Tag Sepsis

Year 2023

Keywords

sepsis

septic shock

mortality rates

treatment practices

research

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