SCCM Resource Library-Timely Cessation of Proton Pump Inhibitors in Critically Ill Patients Impacts Morbidity and Mortality: A Propensity Score Matched Cohort Study (CCM)

Timely Cessation of Proton Pump Inhibitors in Critically Ill Patients Impacts Morbidity and Mortality: A Propensity Score Matched Cohort Study (CCM)

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Video Summary

The study investigates the impact of prolonged proton pump inhibitor (PPI) therapy beyond hospital discharge in critically ill ICU patients. It finds that a significant proportion (41.7%) of these patients continued PPI therapy without indication, leading to increased morbidity and mortality. Specifically, this unnecessary continuation was linked to a 35% higher risk of re-hospitalization within the first year and a 17% increased mortality risk over two years. The research highlights the need for ICU physicians to ensure timely cessation of PPI therapy to avoid adverse effects and unnecessary overtreatment.

Asset Caption

One-Hour Concurrent Session | Late-Breaking Studies Affecting Patient Outcomes II

Meta Tag

Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

proton pump inhibitors

ICU patients

morbidity and mortality

therapy cessation

overtreatment

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