SCCM Resource Library-When Less Use of Extracorporeal Therapy Is Better: ECCO2R

Video Transcription

Video Summary

In this video, Prof. Thomas Zagmani discusses the use of extracorporeal CO2 removal in patients with hypoxemic respiratory failure. The REST trial, conducted in 51 NHS hospitals, aimed to determine if this technique could reduce 90-day mortality. The trial included 412 patients, but was stopped early due to fatal intracranial hemorrhages. An interim analysis showed no significant difference in mortality between the two groups. The trial concluded that routine use of extracorporeal CO2 removal is not recommended in acute hypoxemic respiratory failure. It is suggested that less invasive procedures allow for more use of evidence-based interventions in these cases.

Asset Subtitle

Pulmonary, Procedures, 2022

Asset Caption

This session will explore when less intervention means better outcomes in mechanical ventilation. The session will be centered around less use of muscle relaxants (ROSE trial), less use of extracorporeal carbon dioxide removal (REST trial) and less use of fluids.

Meta Tag

Content Type Presentation

Knowledge Area Pulmonary

Knowledge Area Procedures

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Respiratory Failure

Tag Mechanical Ventilation

Year 2022

Keywords

Prof. Thomas Zagmani

extracorporeal CO2 removal

hypoxemic respiratory failure

REST trial

90-day mortality

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