SCCM Resource Library-Year in Review: Internal Medicine

Video Transcription

Video Summary

The speaker discusses the biggest papers of the year focused on COVID-19 critical illness, specifically new therapies for COVID-19 that target the host response to infection. They focus on three aspects: steroids, anti-interleukin-6 therapies, and Janus kinase inhibitors. In the first year of the pandemic, treatment for severe COVID-19 was limited to supportive care, such as oxygen and ventilation, and the antiviral drug remdesivir. However, in 2021, specific treatments emerged that benefit patients with severe COVID-19, including steroids, interleukin-6 antagonists, and Janus kinase inhibitors. The speaker reviews the results of the recovery study, which showed a significant mortality benefit of dexamethasone, and the REMAP-CAP study, which demonstrated a benefit of tocilizumab and seralomab in reducing organ support and mortality. They also discuss the COVE barrier study, which showed that Baricitinib did not decrease mortality but had a significant mortality benefit in invasively mechanically ventilated patients with COVID-19. Finally, the speaker highlights the importance of post-ICU care and the long-term effects of sepsis, including physical, mental, and cognitive challenges. They discuss the growing number of post-ICU and post-COVID clinics that have emerged to address these challenges.

Asset Subtitle

Professional Development and Education, 2022

Asset Caption

This session will highlight the latest research, lessons learned, and changes taking place in critical care internal medicine practice during the past year.

Learning Objectives:
-Showcase high-impact published studies during the past year
-Discuss the importance of each study and how it could impact practice in critical care medicine
-Discuss case studies

Meta Tag

Content Type Presentation

Knowledge Area Professional Development and Education

Knowledge Level Foundational

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Professional Development

Tag Evidence Based Medicine

Year 2022

Keywords

COVID-19 critical illness

new therapies

steroids

anti-interleukin-6 therapies

Janus kinase inhibitors

supportive care

remdesivir

recovery study

post-ICU care

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