SCCM Resource Library-Year in Review: Neuroscience: Pharmacology Research Update 2

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Video Summary

The presentation discussed several significant studies from 2023 in neurocritical care medicine, focusing on their findings and limitations. The BEST-2 and Optimal BP trials examined blood pressure management after mechanical thrombectomy for ischemic stroke, finding no clear benefit or harm from lower systolic blood pressure targets. The INTERACT-3 trial explored a bundled care approach for intracerebral hemorrhage, showing potential improvement in outcomes with early aggressive treatment. The Early Drain trial indicated that adding a lumbar drain to standard care in subarachnoid hemorrhage patients might reduce unfavorable outcomes. Lastly, the RESCUE-ASDH study compared craniotomy and craniectomy for acute subdural hematoma, finding no significant differences in primary outcomes but noting variations in secondary outcomes, like wound infections and additional surgeries. Limitations included issues like data generalizability, patient condition disparities, and intervention timing across these studies.

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Year in Review | Year in Review: Neuroscience

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Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

neurocritical care

ischemic stroke

intracerebral hemorrhage

subarachnoid hemorrhage

acute subdural hematoma

clinical trials 2023

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