Transplant Triumph: Caring for the Transplant Recipients in the ICU-Transplant Triumph Caring for Transplant Recipients in the ICU

Video Transcription

Video Summary

The webcast titled "Transplant Triumph: Caring for Transplant Recipients in the ICU," moderated by Eric Harvester from the Cleveland Clinic, featured speakers Dr. Bashir Hamade and Dr. Robert Page. The discussions primarily focused on post-operative care for liver and heart transplant recipients in the ICU, highlighting medical management and pharmacological considerations.<br /><br />Dr. Hamade covered orthotopic liver transplant (OLT) care, emphasizing pain management, coagulopathy, complications like respiratory insufficiency, and renal disorders in post-operative liver transplant patients. Key points included the importance of thromboelastography for targeted resuscitation in bleeding patients, avoiding NSAIDs due to renal risks, and understanding immunosuppressants' roles, such as calcineurin inhibitors and their side effects, including nephrotoxicity and potential for neurotoxicity.<br /><br />For heart transplant care, Dr. Page discussed right heart failure, postoperative vasoplegia, hemodynamic management, and the complexity of pharmacokinetics among ICU medications. Page highlighted the need for constant adjustments of immunosuppressants like Tercrolimus based on interacting drugs and patient-specific conditions. The issues of primary graft dysfunction and handling atypical post-operative conditions like PRESS (posterior reversible encephalopathy syndrome) were addressed, urging close monitoring.<br /><br />Both experts underscored the importance of personalized, institution-specific practices in transplant care and maintaining robust interdisciplinary communication. A thorough understanding of drug interactions, especially concerning common medications and immunosuppressive therapies, is critical to optimize outcomes for transplant recipients in the ICU setting. The presentations concluded with a Q&A session addressing post-operative complication practices and standardizing procedures for medication administration adjustments.

Keywords

transplant care

ICU management

liver transplant

heart transplant

immunosuppressants

pharmacological considerations

post-operative complications

interdisciplinary communication

personalized medicine

medication interactions

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